The most frequently observed adverse reactions during the current vaccination campaign are fever, headache, muscle or joint pain, injection site reactions and fatigue. These are non-serious reactions, of mild or moderate severity which, although annoying, resolve in a few hours or a few days, often without even resorting to symptomatic treatments (painkiller or similar).
As with all medicines, allergic reactions up to anaphylactic shock are also possible, although very rare. For this reason, vaccinations are carried out in a safe environment by trained personnel, and there is an observation period of at least 15 minutes after vaccination. Another aspect that is taken into account is that, following the injection, anxious reactions may also occur, with vaso-vagal phenomena ranging from the sensation of being about to faint up to actual fainting, so the staff pay attention to avoid fall injuries.
Monitoring of adverse reactions is described in the monthly surveillance reports available here.