Glatiramer acetate: Anaphylactic reactions may occur months up to years after treatment initiation.

Summary:

• Anaphylactic reactions may occur shortly following administration of glatiramer acetate even months up to years after initiation of treatment. Cases with a fatal outcome have been reported.
• Advise patients and/or caregivers on the signs and symptoms of anaphylactic reactions and to seek immediate emergency medical care in the event of an anaphylactic reaction. 
• If an anaphylactic reaction occurs, treatment with glatiramer acetate must be discontinued.