The Italian Medicines Agency has published the 2025 Independent Research Call on rare diseases, with a budget of EUR 17,800,000 for the promotion of studies on low-prevalence diseases, which often do not attract significant commercial investment. 

Researchers may submit their proposals electronically starting at 10:00 a.m. on Monday, 9 June 2025, by following the instructions that will be published on the AIFA website. The deadline is Wednesday 23 July 2025 at 12 noon.